Comparing the effectiveness of magnesium oxide and naldemedine in preventing opioid-induced constipation: a proof of concept, single institutional, two arm, open-label, phase II, randomized controlled trial: the MAGNET study

BACKGROUND: Patients taking opioids are known to develop opioid-induced constipation (OIC), which reduces their quality of life. The aim of this study is to compare magnesium oxide with naldemedine and determine which is more effective in preventing OIC. METHODS: This proof-of-concept, prospective,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Trials
Egile Nagusiak: Ozaki, Anna, Kessoku, Takaomi, Iwaki, Michihiro, Kobayashi, Takashi, Yoshihara, Tsutomu, Kato, Takayuki, Honda, Yasushi, Ogawa, Yuji, Imajo, Kento, Higurashi, Takuma, Yoneda, Masato, Taguri, Masataka, Yamanaka, Takeharu, Ishiki, Hiroto, Kobayashi, Noritoshi, Saito, Satoru, Ichikawa, Yasushi, Nakajima, Atsushi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Study Protocol
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268242/
https://ncbi.nlm.nih.gov/pubmed/32487150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04385-0
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