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Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination

Active membrane remodeling during myelination relies on phospholipid synthesis and membrane polarization, both of which are known to depend on inositol phospholipids. Here, we show that sciatic nerves of mice lacking phosphatidylinositol 4-kinase alpha (PI4KA) in Schwann cells (SCs) show substantial...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Alvarez-Prats, Alejandro, Bjelobaba, Ivana, Aldworth, Zane, Baba, Takashi, Abebe, Daniel, Kim, Yeun Ju, Stojilkovic, Stanko S., Stopfer, Mark, Balla, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268203/
https://ncbi.nlm.nih.gov/pubmed/29874576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.019
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