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Lou Gehrig’s Disease (ALS): UBQLN2 Mutations Strike Out of Phase
In this issue of Structure, Dao et al. (2019) report that ALS-linked mutations in the Pxx domain of Ubiquilin 2 (UBQLN2) differentially influence the protein’s phase separation abilities. The affect is by reducing the temperature and UBQLN2 concentration necessary for liquid-liquid phase separation...
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| Yayımlandı: | Structure |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7267892/ https://ncbi.nlm.nih.gov/pubmed/31167121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.05.006 |
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