Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

IMPORTANCE: Antibiotic overuse drives antibiotic resistance. Gram-negative bacteremia is a common infection that results in substantial antibiotic use. OBJECTIVE: To compare the clinical effectiveness of C-reactive protein (CRP)–guided, 7-day, and 14-day antibiotic durations 30, 60, and 90 days afte...

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Veröffentlicht in:JAMA
Hauptverfasser: von Dach, Elodie, Albrich, Werner C., Brunel, Anne-Sophie, Prendki, Virginie, Cuvelier, Clémence, Flury, Domenica, Gayet-Ageron, Angèle, Huttner, Benedikt, Kohler, Philipp, Lemmenmeier, Eva, McCallin, Shawna, Rossel, Anne, Harbarth, Stephan, Kaiser, Laurent, Bochud, Pierre-Yves, Huttner, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Medical Association 2020
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267846/
https://ncbi.nlm.nih.gov/pubmed/32484534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.6348
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