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MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing and PCR errors

SUMMARY: The development of de novo DNA synthesis, polymerase chain reaction (PCR), DNA sequencing and molecular cloning gave researchers unprecedented control over DNA and DNA-mediated processes. To reduce the error probabilities of these techniques, DNA composition has to adhere to method-dependen...

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Vydáno v:Bioinformatics
Hlavní autoři: Schwarz, Michael, Welzel, Marius, Kabdullayeva, Tolganay, Becker, Anke, Freisleben, Bernd, Heider, Dominik
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267826/
https://ncbi.nlm.nih.gov/pubmed/32129840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa140
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