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A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance

Multidrug resistance (MDR) to chemotherapeutic drugs remains one of the major impediments to the treatment of cancer. Discovery and development of drugs that can prevent and reverse the acquisition of multidrug resistance constitute a foremost challenge in cancer therapeutics. In this work, we scree...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zahra, Rida, Furqan, Muhammad, Ullah, Rahim, Mithani, Aziz, Saleem, Rahman Shah Zaib, Faisal, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266297/
https://ncbi.nlm.nih.gov/pubmed/32484843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233993
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