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Hypermethylation of the miR-155 gene in the whole blood and decreased plasma level of miR-155 in rheumatoid arthritis

OBJECTIVES: miR-155 plays a critical role in the inflammatory process and in diseases such as rheumatoid arthritis (RA). miR155 gene expression is regulated by its gene promoter region CpG island methylation. Previous studies have shown inconsistent changes in circulating levels of mir-155 in RA pat...

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Publié dans:PLoS One
Auteurs principaux: Kolarz, Bogdan, Ciesla, Marek, Dryglewska, Magdalena, Rosenthal, Ann K., Majdan, Maria
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266293/
https://ncbi.nlm.nih.gov/pubmed/32484820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233897
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