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Concordance between TP53 alterations in blood and tissue: impact of time interval, biopsy site, cancer type and circulating tumor DNA burden

We examined the impact of spatial, temporal, histologic, and quantitative factors on concordance between TP53 alterations in tissue DNA vs in circulating tumor DNA (ctDNA). Four hundred and thirty‐three patients underwent next‐generation sequencing (NGS) in which both tissue and blood samples were e...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Bieg‐Bourne, Cheyennedra C., Okamura, Ryosuke, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266274/
https://ncbi.nlm.nih.gov/pubmed/32187847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12672
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