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Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction

Osimertinib, a third‐generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI), provides marked clinical benefit for patients with EGFR‐activating mutations. Unfortunately, limited treatments exist for patients who acquire osimertinib resistance. We observed two ‘...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Han, Rui, Hao, Shuai, Lu, Conghua, Zhang, Chong, Lin, Caiyu, Li, Li, Wang, Yubo, Hu, Chen, He, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266273/
https://ncbi.nlm.nih.gov/pubmed/32239624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12682
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