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Investigational plasma kallikrein inhibitors for the treatment of diabetic macular edema: an expert assessment
INTRODUCTION: Plasma kallikrein is a mediator of vascular leakage and inflammation. Activation of plasma kallikrein can induce features of diabetic macular edema (DME) in preclinical models. Human vitreous shows elevated plasma kallikrein levels in patients with DME. Because of the incomplete respon...
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| Publicado no: | Expert Opin Investig Drugs |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265898/ https://ncbi.nlm.nih.gov/pubmed/31985300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2020.1723078 |
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