Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms

Malaria parasites complete their intra-erythrocytic developmental cycle (IDC) in multiples of 24 h suggesting a circadian basis, but the mechanism controlling this periodicity is unknown. Combining in vivo and in vitro approaches utilizing rodent and human malaria parasites, we reveal that: (i) 57%...

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Udgivet i:Nat Commun
Main Authors: Subudhi, Amit K., O’Donnell, Aidan J., Ramaprasad, Abhinay, Abkallo, Hussein M., Kaushik, Abhinav, Ansari, Hifzur R., Abdel-Haleem, Alyaa M., Ben Rached, Fathia, Kaneko, Osamu, Culleton, Richard, Reece, Sarah E., Pain, Arnab
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265539/
https://ncbi.nlm.nih.gov/pubmed/32488076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16593-y
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