A unique hybrid characteristic having both pro- and anti-inflammatory phenotype transformed by repetitive low-dose lipopolysaccharide in C8-B4 microglia

Although lipopolysaccharide (LPS) is regarded as an inducer of inflammation, previous studies have suggested that repetitive low-dose LPS has neuroprotective effects via immunomodulation of microglia, resident macrophages of brain. However, microglia transformed by the stimulus of repetitive low-dos...

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Vydáno v:Sci Rep
Hlavní autoři: Mizobuchi, Haruka, Yamamoto, Kazushi, Tsutsui, Shoko, Yamashita, Masafumi, Nakata, Yoko, Inagawa, Hiroyuki, Kohchi, Chie, Soma, Gen-Ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265460/
https://ncbi.nlm.nih.gov/pubmed/32488176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65998-8
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