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KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling

Primary cilia play critical roles in development and disease. Their assembly and disassembly are tightly coupled to cell cycle progression. Here, we present data identifying KIF14 as a regulator of cilia formation and Hedgehog (HH) signaling. We show that RNAi depletion of KIF14 specifically leads t...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Pejskova, Petra, Reilly, Madeline Louise, Bino, Lucia, Bernatik, Ondrej, Dolanska, Linda, Ganji, Ranjani Sri, Zdrahal, Zbynek, Benmerah, Alexandre, Cajanek, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265313/
https://ncbi.nlm.nih.gov/pubmed/32348467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904107
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