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Blood clots and TAM receptor signalling in COVID-19 pathogenesis

We suggest that the exuberant blood clotting and immune hyper-reaction seen in patients with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand for the immunosuppressive TAM...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Lemke, Greg, Silverman, Gregg J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264968/
https://ncbi.nlm.nih.gov/pubmed/32488201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-0354-x
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