Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey

BACKGROUND: Target-specific anticancer drugs are under rapid development. Little is known, however, about the risk of administering target-specific drugs to patients who have tumours with molecular alterations or other characteristics that can make the drug ineffective or even harmful. An increasing...

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Vydáno v:BMJ Open
Hlavní autoři: Schandelmaier, Stefan, Schmitt, Andreas M, Herbrand, Amanda K, Glinz, Dominik, Ewald, Hannah, Briel, Matthias, Guyatt, Gordon H, Hemkens, Lars G, Kasenda, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264639/
https://ncbi.nlm.nih.gov/pubmed/32474426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-034565
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