Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations

Both the accumulation of Amyloid-β (Aβ) in plaques and phosphorylation of Tau protein (p-Tau) in neurofibrillary tangles have been identified as two major symptomatic features of Alzheimer's disease (AD). Despite of critical role of Aβ and p-Tau in AD progress, the interconnection of signalling...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Cap, Kim Cuong, Jung, Yeon-Joo, Choi, Bo Young, Hyeon, Seung Jae, Kim, Jae-Gyu, Min, Jung-Ki, Islam, Rokibul, Hossain, Abu Jubayer, Chung, Won-Suk, Suh, Sang Won, Ryu, Hoon, Park, Jae-Bong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264465/
https://ncbi.nlm.nih.gov/pubmed/32046944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101446
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