Targeted Metabolic Reprogramming to Improve the Efficacy of Oncolytic Virus Therapy

Oncolytic viruses (OVs) represent a promising new class of cancer therapeutics and cause antitumor effects by two major mechanisms: (1) directly killing cancer cells in a process known as oncolysis, or (2) initiating a powerful antitumor immune response. Interestingly, energy metabolism, within eith...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Kennedy, Barry E., Sadek, Maryanne, Gujar, Shashi A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264427/
https://ncbi.nlm.nih.gov/pubmed/32243836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.03.014
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