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Targeted Metabolic Reprogramming to Improve the Efficacy of Oncolytic Virus Therapy

Oncolytic viruses (OVs) represent a promising new class of cancer therapeutics and cause antitumor effects by two major mechanisms: (1) directly killing cancer cells in a process known as oncolysis, or (2) initiating a powerful antitumor immune response. Interestingly, energy metabolism, within eith...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Kennedy, Barry E., Sadek, Maryanne, Gujar, Shashi A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264427/
https://ncbi.nlm.nih.gov/pubmed/32243836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.03.014
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