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Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

Genome editing tools have already revolutionized biomedical research and are also expected to have an important impact in the clinic. However, their extensive use in research has revealed much unpredictability, both off and on target, in the outcome of their application. We discuss the challenges as...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Teboul, Lydia, Herault, Yann, Wells, Sara, Qasim, Waseem, Pavlovic, Guillaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264426/
https://ncbi.nlm.nih.gov/pubmed/32243835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.03.015
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