Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 and Pfcoronin molecular markers in treatment failure in Senegal

In 2006, Senegal adopted artemisinin-based combination therapy (ACT) as first-line treatment in the management of uncomplicated malaria. This study aimed to update the status of antimalarial efficacy more than ten years after their first introduction. This was a randomized, three-arm, open-label stu...

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Udgivet i:Sci Rep
Main Authors: Diallo, Mamadou Alpha, Yade, Mamadou Samb, Ndiaye, Yaye Die, Diallo, Ibrahima, Diongue, Khadim, Sy, Saidou Abdoul, Sy, Mouhamad, Seck, Mame Cheikh, Ndiaye, Mouhamadou, Dieye, Baba, Gomis, Jules François, Sow, Djiby, Dème, Awa Bineta, Badiane, Aida Sadikh, Ndiaye, Daouda
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264303/
https://ncbi.nlm.nih.gov/pubmed/32483161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65553-5
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