Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur. How these factors act together in time and space, and which cell types produce these factors is not understood. Here we assess the function of Adamt...

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Publicat a:Nat Commun
Autors principals: Wang, Guangxia, Muhl, Lars, Padberg, Yvonne, Dupont, Laura, Peterson-Maduro, Josi, Stehling, Martin, le Noble, Ferdinand, Colige, Alain, Betsholtz, Christer, Schulte-Merker, Stefan, van Impel, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264274/
https://ncbi.nlm.nih.gov/pubmed/32483144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16552-7
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