Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur. How these factors act together in time and space, and which cell types produce these factors is not understood. Here we assess the function of Adamt...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Guangxia, Muhl, Lars, Padberg, Yvonne, Dupont, Laura, Peterson-Maduro, Josi, Stehling, Martin, le Noble, Ferdinand, Colige, Alain, Betsholtz, Christer, Schulte-Merker, Stefan, van Impel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264274/
https://ncbi.nlm.nih.gov/pubmed/32483144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16552-7
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