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Differentially Regulated Transcription Factors and ABC Transporters in a Mitochondrial Dynamics Mutant Can Alter Azole Susceptibility of Aspergillus fumigatus

Azole resistance of the fungal pathogen Aspergillus fumigatus is an emerging problem. To identify novel mechanisms that could mediate azole resistance in A. fumigatus, we analyzed the transcriptome of a mitochondrial fission/fusion mutant that exhibits increased azole tolerance. Approximately 12% of...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Sturm, Laura, Geißel, Bernadette, Martin, Ronny, Wagener, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264269/
https://ncbi.nlm.nih.gov/pubmed/32528443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01017
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