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Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future Directions

Cellular senescence refers to a cellular phenotype characterized by an altered transcriptome, pro-inflammatory secretome, and generally irreversible growth arrest. Acutely senescent cells are widely recognized as performing key physiological functions in vivo promoting normal organogenesis, successf...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Docherty, Marie Helena, Baird, David P., Hughes, Jeremy, Ferenbach, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264097/
https://ncbi.nlm.nih.gov/pubmed/32528288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00755
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