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Protective effect of high-affinity liposomes encapsulating astaxanthin against corneal disorder in the in vivo rat dry eye disease model

Oxidative stress induced by decreases in tear volume and excessive tear evaporation is a key factor in dry eye disease (DED). Previously, we reported that desiccation stress induces reactive oxygen species generation and up-regulated expression of age-related markers such as p53, p21 and p16. We als...

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Bibliographic Details
Published in:J Clin Biochem Nutr
Main Authors: Shimokawa, Tatsuharu, Fukuta, Tatsuya, Inagi, Toshio, Kogure, Kentaro
Format: Artigo
Language:Inglês
Published: the Society for Free Radical Research Japan 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263926/
https://ncbi.nlm.nih.gov/pubmed/32523249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.19-102
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