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Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation

Eosinophilic esophagitis (EoE) is a T-helper 2 (Th2), eosinophilic disease associated with pathologic tissue remodeling that leads to end-organ dysfunction. During early-stage disease, inflammation and subepithelial fibrosis are coupled and reversible, but in late-stage or therapy-resistant disease,...

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Publicat a:Clin Transl Gastroenterol
Autors principals: Nhu, Quan M., Hsieh, Lance, Dohil, Lucas, Dohil, Ranjan, Newbury, Robert O., Kurten, Richard, Moawad, Fouad J., Aceves, Seema S.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263661/
https://ncbi.nlm.nih.gov/pubmed/32352681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ctg.0000000000000164
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