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Taming Amphotericin B

A strategy is introduced for enhancing the cellular selectivity of Amphotericin B (AmB) and other classes of membrane-disrupting agents. This strategy involves attaching the agent to a molecular umbrella to minimize the disruptive power of aggregated forms. Based on this approach, AmB has been coupl...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Janout, Vaclav, Schell, Wiley A., Thévenin, Damien, Yu, Yuming, Perfect, John R., Regen, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263395/
https://ncbi.nlm.nih.gov/pubmed/26340430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00463
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