During Aspergillus Infection, Monocyte-Derived DCs, Neutrophils, and Plasmacytoid DCs Enhance Innate Immune Defense through CXCR3-Dependent Crosstalk

Aspergillus fumigatus, a ubiquitous mold, is a common cause of invasive aspergillosis (IA) in immunocompromised patients. Host defense against IA relies on lung-infiltrating neutrophils and monocyte-derived dendritic cells (Mo-DCs). Here, we demonstrate that plasmacytoid dendritic cells (pDCs), whic...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Guo, Yahui, Kasahara, Shinji, Jhingran, Anupam, Tosini, Nicholas L., Zhai, Bing, Aufiero, Mariano A., Mills, Kathleen A.M., Gjonbalaj, Mergim, Espinosa, Vanessa, Rivera, Amariliz, Luster, Andrew D., Hohl, Tobias M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263227/
https://ncbi.nlm.nih.gov/pubmed/32485165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.05.002
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