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Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

Biofilms formed by the fungal pathogen Candida albicans are resistant to many of the antifungal agents commonly used in the clinic. Previous reports suggest that protease inhibitors, specifically inhibitors of aspartyl proteases, could be effective antibiofilm agents. We screened three protease inhi...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Lohse, Matthew B., Gulati, Megha, Craik, Charles S., Johnson, Alexander D., Nobile, Clarissa J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261846/
https://ncbi.nlm.nih.gov/pubmed/32523574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01027
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