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Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

Biofilms formed by the fungal pathogen Candida albicans are resistant to many of the antifungal agents commonly used in the clinic. Previous reports suggest that protease inhibitors, specifically inhibitors of aspartyl proteases, could be effective antibiofilm agents. We screened three protease inhi...

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Bibliografski detalji
Izdano u:Front Microbiol
Glavni autori: Lohse, Matthew B., Gulati, Megha, Craik, Charles S., Johnson, Alexander D., Nobile, Clarissa J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261846/
https://ncbi.nlm.nih.gov/pubmed/32523574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01027
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