Superior Antitumor Efficacy of IFN-α2b-Incorporated Photo-Cross-Linked Hydrogels Combined with T Cell Transfer and Low-Dose Irradiation Against Gastric Cancer

INTRODUCTION: The exhaustion and poor homing of activated lymphocytes are critical obstacles in adoptive cell immunotherapy for solid tumors. In order to effectively deliver immune cells into tumors, we encapsulated interferon-α2b (IFN-α2b) into macroporous hydrogels as an enhancement factor and uti...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Liu, Qin, Zhang, Dinghu, Qian, Hanqing, Chu, Yanhong, Yang, Yan, Shao, Jie, Xu, Qiuping, Liu, Baorui
Format: Artigo
Language:Inglês
Published: Dove 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261665/
https://ncbi.nlm.nih.gov/pubmed/32547021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S249174
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