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Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA

RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-documented machinery that plays a role in mtRNA decay in humans is the complex of polynucleotide phosphorylase (PNPase) and SUV3 helicase, forming the degradosome. REXO2, a homolog of prokaryotic oligoribonucleases pr...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Szewczyk, Maciej, Malik, Deepshikha, Borowski, Lukasz S, Czarnomska, Sylwia D, Kotrys, Anna V, Klosowska-Kosicka, Kamila, Nowotny, Marcin, Szczesny, Roman J
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261184/
https://ncbi.nlm.nih.gov/pubmed/32365187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa302
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