β-Arrestin2 is a critical component of the GPCR–eNOS signalosome

Endothelial cell nitric oxide (NO) synthase (eNOS), the enzyme responsible for synthesis of NO in endothelial cells, is regulated by complex posttranslational mechanisms. Sinusoidal portal hypertension, a disorder characterized by liver sinusoidal endothelial cell (SEC) injury with resultant reduced...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Liu, Songling, Luttrell, Louis M., Premont, Richard T., Rockey, Don C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261012/
https://ncbi.nlm.nih.gov/pubmed/32404425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922608117
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