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The corrected gene proximity map for analyzing the 3D genome organization using Hi-C data

BACKGROUND: Genome-wide ligation-based assays such as Hi-C provide us with an unprecedented opportunity to investigate the spatial organization of the genome. Results of a typical Hi-C experiment are often summarized in a chromosomal contact map, a matrix whose elements reflect the co-location frequ...

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Publicat a:BMC Bioinformatics
Autors principals: Ye, Cheng, Paccanaro, Alberto, Gerstein, Mark, Yan, Koon-Kiu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260828/
https://ncbi.nlm.nih.gov/pubmed/32471347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03545-y
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