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How are missing data in covariates handled in observational time-to-event studies in oncology? A systematic review

BACKGROUND: Missing data in covariates can result in biased estimates and loss of power to detect associations. It can also lead to other challenges in time-to-event analyses including the handling of time-varying effects of covariates, selection of covariates and their flexible modelling. This revi...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Carroll, Orlagh U., Morris, Tim P., Keogh, Ruth H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260743/
https://ncbi.nlm.nih.gov/pubmed/32471366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01018-7
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