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Replacing CAR-T cell resistance with persistence by changing a single residue
Sustained persistence of chimeric antigen receptor T (CAR-T) cells is a key characteristic associated with long-term remission in patients with hematologic malignancies. Attempts to uncover mechanisms that enhance persistence and thus functionality will have a substantial impact in broadening applic...
Gorde:
| Argitaratua izan da: | J Clin Invest |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Clinical Investigation
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260020/ https://ncbi.nlm.nih.gov/pubmed/32364534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136872 |
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