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Norrin mediates opposing effects on tumor progression of glioblastoma stem cells

Glioblastoma is the most common human brain cancer entity and is maintained by a glioblastoma stem cell (GSC) subpopulation. In this issue of the JCI, El-Sehemy and colleagues explored the effects that Norrin, a well-characterized activator of Wnt/β-catenin signaling, had on tumor growth. Norrin inh...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Kassumeh, Stefan, Priglinger, Siegfried G., Ohlmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259986/
https://ncbi.nlm.nih.gov/pubmed/32391807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137254
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