Differential effects of Fe(2+) and Fe(3+) on osteoblasts and the effects of 1,25(OH)(2)D(3), deferiprone and extracellular calcium on osteoblast viability under iron-overloaded conditions

One of the potential contributing factors for iron overload-induced osteoporosis is the iron toxicity on bone forming cells, osteoblasts. In this study, the comparative effects of Fe(3+) and Fe(2+) on osteoblast differentiation and mineralization were studied in UMR-106 osteoblast cells by using fer...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Lertsuwan, Kornkamon, Nammultriputtar, Ketsaraporn, Nanthawuttiphan, Supanan, Tannop, Natnicha, Teerapornpuntakit, Jarinthorn, Thongbunchoo, Jirawan, Charoenphandhu, Narattaphol
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259719/
https://ncbi.nlm.nih.gov/pubmed/32470038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234009
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