PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer

OBJECTIVES: The present study aims to elucidate the underlying mechanism how PFKP is regulated by BRCA1 and the clinical significance of PFKP in breast cancer. METHODS: MEF-BRCA1(△/△) and the wild type counterpart MEF-BRCA1(+/+) cell lines were used to test the sensitivity of glucose depletion in cu...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Yeerken, Danna, Hong, Ruoxi, Wang, Yan, Gong, Ying, Liu, Rui, Yang, Di, Li, Jinting, Fan, Jiawen, Chen, Jie, Zhang, Weimin, Zhan, Qimin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259711/
https://ncbi.nlm.nih.gov/pubmed/32470015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233750
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