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Bone marrow is the preferred site of memory CD4(+) T cell proliferation during recovery from sepsis

Sepsis survivors suffer from increased vulnerability to infections, and lymphopenia presumably contributes to this problem. The mechanisms of the recovery of memory CD4(+) T cells after sepsis remain elusive. We used the cecal ligation and puncture mouse model of sepsis to study the restoration of t...

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Skirecki, Tomasz, Swacha, Patrycja, Hoser, Grażyna, Golab, Jakub, Nowis, Dominika, Kozłowska, Ewa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259529/
https://ncbi.nlm.nih.gov/pubmed/32434988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134475
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