Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies

INTRODUCTION: In this study, the encapsulation of fentanyl citrate as an opioid drug with hydrophobic nature in the nanostructured lipid carrier (NLC) is performed. METHODS: For encapsulation of fentanyl citrate drug, hot homogenization method is used. The pharmacokinetics of encapsulated fentany...

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Publicado en:Drug Des Devel Ther
Autores principales: Bahrami, Mohammad Amin, Farhadian, Nafiseh, Karimi, Mohammad, Forouzan, Arash, Masoumi, Kambiz
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2020
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259451/
https://ncbi.nlm.nih.gov/pubmed/32546968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S235474
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