Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial

Development of semi-automated devices that can reduce the hands-on time and standardize the production of clinical-grade CAR T-cells, such as CliniMACS Prodigy from Miltenyi, is key to facilitate the development of CAR T-cell therapies, especially in academic institutions. However, the feasibility o...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Castella, Maria, Caballero-Baños, Miguel, Ortiz-Maldonado, Valentín, González-Navarro, Europa Azucena, Suñé, Guillermo, Antoñana-Vidósola, Asier, Boronat, Anna, Marzal, Berta, Millán, Lucía, Martín-Antonio, Beatriz, Cid, Joan, Lozano, Miquel, García, Enric, Tabera, Jaime, Trias, Esteve, Perpiña, Unai, Canals, Josep Ma, Baumann, Tycho, Benítez-Ribas, Daniel, Campo, Elías, Yagüe, Jordi, Urbano-Ispizua, Álvaro, Rives, Susana, Delgado, Julio, Juan, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259426/
https://ncbi.nlm.nih.gov/pubmed/32528460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00482
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