Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workup

STUDY QUESTION: Can maternal plasma cell-free DNA (cfDNA) detect chromosomal anomalies in early pregnancy loss (EPL) and recurrent pregnancy loss (RPL)? SUMMARY ANSWER: Genome-wide cfDNA testing can serve as an alternative to cytogenetic analysis in products of conception (POCs) in RPLs and can guid...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Yaron, Yuval, Pauta, Montse, Badenas, Celia, Soler, Anna, Borobio, Virginia, Illanes, Carmen, Paz-y-Miño, Fernanda, Martinez-Portilla, Raigam, Borrell, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259365/
https://ncbi.nlm.nih.gov/pubmed/32386059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/deaa073
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