CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury

We tested a newly described molecular memory system, CCR5 signaling, for its role in recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical neurons after stroke. Post-stroke neuronal knockdown of CCR5 in pre-motor cortex leads to early recovery of motor contro...

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Pubblicato in:Cell
Autori principali: Joy, Mary T., Assayag, Einor Ben, Shabashov-Stone, Dalia, Liraz-Zaltsman, Sigal, Mazzitelli, Jose, Arenas, Marcela, Abduljawad, Nora, Kliper, Efrat, Korczyn, Amos D., Thareja, Nikita S., Kesner, Efrat L., Zhou, Miou, Huang, Shan, Silva, Tawnie K., Katz, Noomi, Bornstein, Natan M., Silva, Alcino J., Shohami, Esther, Carmichael, S. Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259116/
https://ncbi.nlm.nih.gov/pubmed/30794775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.01.044
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