Selenoprotein V Protects Against Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis

OBJECTIVES: Selenoprotein V (SELENOV) contains a thioredoxin-like fold and a conserved CxxU motif with a potential redox function. Three experiments were performed to assess its in vivo and in vitro roles and mechanisms in coping with different oxidant insults. METHODS: In Expt.1, SELENOV knockout (...

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Veröffentlicht in:Curr Dev Nutr
Hauptverfasser: Zhang, Xu, Xiong, Wei, Huang, Jiaqiang, Lei, Xin Gen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Vitamins and Minerals
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259104/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa067_085
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