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Mitochondrial Respiration in Female Zucker Rats: Effects of Obesity and Short-Term Metformin Treatment

OBJECTIVES: As childhood obesity rates climb, so has the incidence of type 2 diabetes among children and adolescents. Metformin, an FDA approved anti-hyperglycemic drug, is thought to target the mitochondria, but its effects on mitochondrial function in obesity have not been well studied. We used an...

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Bibliografske podrobnosti
izdano v:Curr Dev Nutr
Main Authors: Rose, Shannon, Carvalho, Eugenia, Irby, David, Bennuri, Sirish, Beebe, Alexandria, Hakkak, Reza
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259076/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa063_080
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