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Flavonoids Ameliorate Stress-Induced Depression by Preventing NLRP3 Inflammasome Priming

OBJECTIVES: Chronic stress activates danger-associated molecular patterns (DAMPs), stimulating the NLRP3 inflammasome. NLRP3 activation triggers the release of pro-inflammatory cytokine IL‐1β. The activity of the NLRP3 inflammasome propagates pro-inflammatory signaling cascades implicated in the ons...

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Bibliografiske detaljer
Udgivet i:Curr Dev Nutr
Hovedforfatter: Pasinetti, Giulio
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259049/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa057_047
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