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Flavonoids Ameliorate Stress-Induced Depression by Preventing NLRP3 Inflammasome Priming
OBJECTIVES: Chronic stress activates danger-associated molecular patterns (DAMPs), stimulating the NLRP3 inflammasome. NLRP3 activation triggers the release of pro-inflammatory cytokine IL‐1β. The activity of the NLRP3 inflammasome propagates pro-inflammatory signaling cascades implicated in the ons...
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| Published in: | Curr Dev Nutr |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7259049/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa057_047 |
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