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Astaxanthin Inhibits Alcohol-Induced Inflammation and Oxidative Stress by Mediating the Sirtuin 1 and Histone Deacetylase 4 Axis in Macrophages

OBJECTIVES: We previously demonstrated that astaxanthin (ASTX), a xanthophyll carotenoid, exerts anti-inflammatory and antioxidant properties in macrophages exposed to ethanol. In this study, to gain mechanistic insight, we explored the role of sirtuin 1 (SIRT1) and histone deacetylase 4 (HDAC4) in...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Kang, Hyunju, Park, Young-Ki, Lee, Ji-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258907/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa041_017
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