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Detectable Unmetabolized Folic Acid, and Sufficient Folate and Vitamin B12 Concentrations Are Evident in Canadian Children with Sickle Cell Disease

OBJECTIVES: Canadian children with sickle cell disease (SCD) are routinely supplemented with high-dose folic acid (1 mg/d), synthetic folate, due to increased erythrocyte production and turn-over in the disease. Folate also plays a vital role in one-carbon metabolism. Impairments in this folate-depe...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Williams, Brock, McCartney, Heather, Lamers, Yvonne, Vercauteren, Suzanne, Wu, John, Karakochuk, Crystal
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258174/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa054_172
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