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Nicotine Upregulates Metalloproteinase Function in Vascular Smooth Muscle Cells Inducing Cell Migration

OBJECTIVES: We hypothesize that nicotine plays a role in the progression of atherosclerosis by inducing VSMC phenotypic switching and cell migration from the media to an inner layer–the intima. This forms a new layer called the neointima, which becomes a plaque with a lipid-rich necrotic core and fi...

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Библиографические подробности
Опубликовано в: :Curr Dev Nutr
Главные авторы: Centner, Ann, Cullen, Abigail, Salazar, Gloria
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257522/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa045_009
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