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A Polyphenol-Rich Muscadine Grape Extract Inhibits HER + Breast Cancer and Protects Against Trastuzumab-Induced Cardiotoxicity

OBJECTIVES: Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is characterized by overexpression of the HER2 receptor. Although targeted HER2 drugs such as trastuzumab (TRZ) are effective for some patients, many patients experience resistance and cardiotoxicity, highlighti...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Mackert, Jessica, Gallagher, Patricia, Tallant, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257428/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa044_033
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