Severe Protein Restriction Activates Liver Protein Catabolism and ATF4-CHOP-TRB3 Pathway to Comprensate for Amino Acid Deficiency

OBJECTIVES: Severely low-protein diets (LP) induce behavioral and metabolic changes including a decrease in body weight, an increase in relative food intake (FI) and alterations in hepatic metabolism. During such protein restriction, changes in hepatic anabolic and catabolic protein pathways could t...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Moro, Joanna, Calvez, Juliane, Chaumontet, Catherine, Even, Patrick, Piedcoq, Julien, Khodorova, Nadezda, Loquet, Nathalie, Gaudichon, Claire, Tomé, Daniel, Marniche, Dalila Azzout
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Energy and Macronutrient Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257347/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa049_040
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