NORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial)

BACKGROUND: Preoperative radiochemotherapy (RCT) is recommended in France prior to total mesorectal excision in patients with mid or low locally advanced rectal cancer (LARC) (cT3/T4 and/or N+) because it has been shown to improve local control. Preoperative RCT has also disadvantages including the...

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Podrobná bibliografie
Vydáno v:BMC Cancer
Hlavní autoři: Brouquet, Antoine, Bachet, Jean-Baptiste, Huguet, Florence, Karoui, Mehdi, Artru, Pascal, Sabbagh, Charles, Lefèvre, Jérémie H., Vernerey, Dewi, Mariette, Christophe, Vicaut, Eric, Benoist, Stephane
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257230/
https://ncbi.nlm.nih.gov/pubmed/32471382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06968-1
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